I have just over 900 hours in this game and these are my favourite items (subject to change):
(this is a general top 10, the numbers don't mean i think one item is necessarily better)
- Brimstone

- Soy Milk

- Mr. Dolly

- D Infinity

- Spindown Dice

- Godhead

- Sinus Infection

- Tractor Beam

- Binky

- Broken Modem

(i nabbed all the sprites from the wiki)
And these are my top 10 items, so not the best items in the game just ones I happen to favour. Some might be confused about Soy Milk being on the list, but it's a really fun item and can be very powerful with the right synergies, all you need is a good tear effect or two and decent luck and - BAM - you have boss melting build.
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xX_Dyrk_Nyte_Xx
rock bottom x soymilk my beloved <3
unfortunately for me i haven't had them at the same time yet X_X
by dean; ; Report
Fischi
AHHHH I LOVE TBOI!!!
I have 1500h in tboi on my steam account :3
Soy milk was always one of my favorite items even before repentance and all the new synergies, it's just such a fun item.
admittedly, it took me a while to come around to it haha, but yeah now that i'm used to it it's sooooo good XD
by dean; ; Report